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Article

Breast cancer risk associated with genotypic polymorphism of the mitosis-regulating gene Aurora-A/STK15/BTAK.

International journal of cancer - 10 Jun 2005

Lo Yen-Li, Yu Jyh-Cherng, Chen Shou-Tung, Yang Hsin-Chou, Fann Cathy S J, Mau Yi-Chien, Shen Chen-Yang

Abstract excerpt

Aneuploidy, an abnormal number of chromosomes, is relatively common and occurs early in breast cancer development. This observation supports a breast tumorigenic contribution of mechanisms responsible for maintaining chromosome number stability in which centrosomes play an essential role. We therefore speculated that the Aurora-A/STK15/BTAK gene, implicated in the regulation of centrosome duplication, may be...

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Source

Identifiers

PMID: 15688402
DOI: 10.1002/ijc.20855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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