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Article

Genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 are associated with ovarian cancer susceptibility among Chinese Han women.

Cancer epidemiology - 1 Oct 2013

Zheng Liyuan, Song Aiping, Ruan Yuan, Chen Lan, Liu Dongge, Li Xianghong, Guo Hongyan, Han Jiyuan, Li Yan, Tian Xinxia, Fang Weigang

Abstract excerpt

INTRODUCTION: Centrosome aberrations and cell-cycle deregulation have important implications for ovarian cancer development. The AURKA, BRCA1, CCNE1 and CDK2 genes play pivotal roles in centrosome duplication and cell-cycle regulation. METHODS: Using a haplotype-based analysis, this study aimed to investigate whether genetic polymorphisms in these four genes may contribute to ovarian cancer susceptibility. A...

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Source

Identifiers

PMID: 23787073
DOI: 10.1016/j.canep.2013.04.018

Genes

AURKA
BRCA1
CCNE1
CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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