Genotypic prediction of human immunodeficiency virus type 1 tropism by use of plasma and peripheral blood mononuclear cells in the routine clinical laboratory.

doi:10.1128/JCM.00336-11

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Article

Genotypic prediction of human immunodeficiency virus type 1 tropism by use of plasma and peripheral blood mononuclear cells in the routine clinical laboratory.

Journal of clinical microbiology - 1 Jul 2011

Paar Christian, Geit Maria, Stekel Herbert, Berg Jörg

Abstract excerpt

We developed a sequencing assay for genotypic HIV-1 tropism determination. The assay allows examination of HIV RNA from plasma and HIV DNA from peripheral blood mononuclear cells (PBMC), including PBMC samples from patients with undetectable viral loads. Assessment of 100 pairs of plasma and PBMC...

Topics

DNA, Viral
Genotype
HIV Infections
HIV-1
Humans
Leukocytes, Mononuclear
Molecular Typing
Plasma
RNA, Viral
Sequence Analysis, DNA
Viral Tropism
Virology

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