Article
Factors influencing the sensitivity and specificity of conventional sequencing in human immunodeficiency virus type 1 tropism testing.
Journal of clinical microbiology - 1 Feb 2013
Knapp David J H F, McGovern Rachel A, Dong Winnie, Poon Art F Y, Swenson Luke C, Zhong Xiaoyin, Woods Conan K, Harrigan P Richard
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) V3 loop sequence can be used to infer viral coreceptor use. The effect of input copy number on population-based sequencing of the V3 loop of HIV-1 was examined through replicate deep and population-based sequencing of samples with known tropism, a heter...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
