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Article

Phenotyping methods for determining HIV tropism and applications in clinical settings.

Current opinion in HIV and AIDS - 1 Sept 2012

Raymond Stéphanie, Delobel Pierre, Izopet Jacques

Abstract excerpt

PURPOSE OF REVIEW: HIV-1 enters CD4-expressing cells via one or both of the chemokine receptors CCR5 and CXCR4. Specific CCR5 antagonists are now in clinical use, but only for CCR5-tropic viruses. Hence, several methods have been developed for assessing HIV-1 tropism in patients who are candidates for CCR5 antagonists. This article reviews current data on phenotypic assays of tropism. RECENT FINDINGS: Phenotypic...

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Share to CCR5 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22832712
DOI: 10.1097/COH.0b013e328356f6d7

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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