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Article

Genotypic prediction of human immunodeficiency virus type 1 CRF02-AG tropism.

Journal of clinical microbiology - 1 Jul 2009

Raymond Stéphanie, Delobel Pierre, Mavigner Maud, Cazabat Michelle, Souyris Corinne, Encinas Stéphanie, Sandres-Sauné Karine, Pasquier Christophe, Marchou Bruno, Massip Patrice, Izopet Jacques

Abstract excerpt

We assessed the performance of genotypic algorithms for predicting the tropism of human immunodeficiency virus type 1 coreceptor usage in 52 patients infected with the CRF02-AG subtype. The combined criteria of the 11/25 and net charge rules accurately detected CXCR4-using CRF02-AG viruses, whereas the Geno2pheno tool lacked sensitivity and the position-specific scoring matrix (PSSM) tool WebPSSM lacked specificity.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19439544
DOI: 10.1128/JCM.02439-08
PMCID: PMC2708518

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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