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Article

Genotypic Tropism Testing in HIV-1 Proviral DNA Can Provide Useful Information at Low-Level Viremia.

Journal of clinical microbiology - 1 Sept 2015

Fabeni Lavinia, Berno Giulia, Svicher Valentina, Ceccherini-Silberstein Francesca, Gori Caterina, Bertoli Ada, Mussini Cristina, Lichtner Miriam, Zaccarelli Mauro, Ammassari Adriana, Pinnetti Carmela, Cicalini Stefania, Mastroianni Claudio Maria, Andreoni Massimo, Antinori Andrea, Perno Carlo Federico, Santoro Maria Mercedes

Abstract excerpt

The possibility of performing genotypic tropism testing (GTT) with proviral DNA (pvDNA) even during suppressed viremia would facilitate the use of CCR5 inhibitors as part of switching, simplification, or intensification strategies. Thus, we aimed to evaluate the tropism concordance between plasma RNA and pvDNA samples and to assess which factors could affect possible discrepancies between the two compartments....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26135872
DOI: 10.1128/JCM.00893-15
PMCID: PMC4540948

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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