Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.

The Journal of antimicrobial chemotherapy - 1 Feb 2011

Vandekerckhove Linos, Verhofstede Chris, Demecheleer Els, De Wit Stephane, Florence Eric, Fransen Katrien, Moutschen Michel, Mostmans Wendy, Kabeya Kabamba, Mackie Nicola, Plum Jean, Vaira Dolores, Van Baelen Kurt, Vandenbroucke Ina, Van Eygen Veerle, Van Marck Herwig, Vogelaers Dirk, Geretti Anna Maria, Stuyver Lieven J

Abstract excerpt

BACKGROUND: Determination of HIV-1 tropism is a pre-requisite to the use of CCR5 antagonists. This study evaluated the potential of population genotypic tropism tests (GTTs) in clinical practice, and the correlation with phenotypic tropism tests (PTTs) in patients accessing routine HIV care. METHODS: Forty-nine consecutive plasma samples for which an original Trofile(TM) assay was performed were obtained from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclohexanes
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Infections

Share to Receptors, CCR5

Share to Receptors, CXCR4

Share to Triazoles

Share to Viral Tropism

Source

Open in PubMed Open full text

Identifiers

PMID: 21196489
DOI: 10.1093/jac/dkq458
PMCID: PMC3019088

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.PMID 21196489Read ↗

Update on clinical and methodological recommendations for genotypic determination of HIV tropism to guide the usage of CCR5 antagonists.Semantic proximity Read ↗

HIV population genotypic tropism testing and its clinical significance.Semantic proximity Read ↗

Genotypic Tropism Testing in HIV-1 Proviral DNA Can Provide Useful Information at Low-Level Viremia.Semantic proximity Read ↗

Phenotypic assays for the determination of coreceptor tropism in HIV-1 infected individuals.Semantic proximity Read ↗

[Methods for determination of HIV tropism and their clinical use].Semantic proximity Read ↗

Determination of HIV tropism and its use in the clinical practice.Semantic proximity Read ↗

Comparison of genotypic and phenotypic HIV type 1 tropism assay: results from the screening samples of Cenicriviroc Study 202, a randomized phase II trial in treatment-naive subjects.Semantic proximity Read ↗

Phenotyping methods for determining HIV tropism and applications in clinical settings.Semantic proximity Read ↗

Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotyping.Semantic proximity Read ↗

TROCAI (Tropism Coreceptor Assay Information): a New Phenotypic Tropism Test and Its Correlation with Trofile Enhanced Sensitivity and Genotypic ApproachesSemantic proximity Read ↗

A highly sensitive and specific model for predicting HIV-1 tropism in treatment-experienced patients combining interpretation of V3 loop sequences and clinical parameters.Semantic proximity Read ↗

Performance of genotypic tropism testing in clinical practice using the enhanced sensitivity version of Trofile as reference assay: results from the OSCAR Study Group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.