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Article

Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2011

Lindenbergh-van der Plas Marlon, Brakenhoff Ruud H, Kuik Dirk J, Buijze Marijke, Bloemena Elisabeth, Snijders Peter J F, Leemans C René, Braakhuis Boudewijn J M

Abstract excerpt

PURPOSE: TP53 is a key gene in cellular homeostasis and is frequently mutated in head and neck squamous cell carcinoma (HNSCC). There is a variety of TP53 mutations, each with its own biological and clinical implication. Aim of the study was to assess the prognostic significance of TP53 mutations in HNSCCs and to identify the most relevant mutation. EXPERIMENTAL DESIGN: TP53 mutation status was investigated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21467160
DOI: 10.1158/1078-0432.CCR-11-0183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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