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Article

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

The New England journal of medicine - 20 Dec 2007

Poeta M Luana, Manola Judith, Goldwasser Meredith A, Forastiere Arlene, Benoit Nicole, Califano Joseph A, Ridge John A, Goodwin Jarrard, Kenady Daniel, Saunders John, Westra William, Sidransky David, Koch Wayne M

Abstract excerpt

BACKGROUND: The abrogation of function of the tumor-suppressor protein p53 as a result of mutation of its gene, TP53, is one of the most common genetic alterations in cancer cells. We evaluated TP53 mutations and survival in patients with squamous-cell carcinoma of the head and neck. METHODS: A t...

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Share to Carcinoma, Squamous Cell
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

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Source

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Identifiers

PMID: 18094376
DOI: 10.1056/NEJMoa073770
PMCID: PMC2263014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18094376-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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