Article
The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma.
BMC cancer - 28 Dec 2017
Omura Go, Ando Mizuo, Ebihara Yasuhiro, Saito Yuki, Kobayashi Kenya, Fukuoka Osamu, Akashi Ken, Yoshida Masafumi, Asakage Takahiro, Yamasoba Tatsuya
Abstract excerpt
BACKGROUND: TP53 is the most frequently mutated gene in human cancers. Previous studies reported that TP53 mutations correlated with poor prognoses in patients with head and neck squamous cell carcinoma (HNSCC). However, the relationship between TP53 mutations and hypopharyngeal squamous cell carcinoma (HPSCC) is not known. The current study aimed to evaluate TP53 mutation status as a predictive biomarker in...
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