Article
Specific TP53 mutations predict aggressive phenotype in head and neck squamous cell carcinoma: a retrospective archival study.
Head & neck oncology - 22 Apr 2011
Peltonen Jenni K, Vähäkangas Kirsi H, Helppi Henni M, Bloigu Risto, Pääkkö Paavo, Turpeenniemi-Hujanen Taina
Abstract excerpt
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy in the world in developed countries. Despite the intense research in the area of squamous cell carcinomas of head and neck (HNSCC), long-term survival rate has not changed significantly in this malignancy during recent decades. METHODS: In this study, we focused on TP53 mutations in specific regions, including...
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