Article

The mutational spectrum in whole exon of p53 in oral squamous cell carcinoma: Its clinical implications

2022-08-26

Abstract excerpt

Mutations in p53 are common in human oral squamous cell carcinoma (OSCC). However, in previous analyses, only detection of mutant p53 protein using immunohistochemistry or mutations in some exons have been examined. Full length mutant p53 protein in many cases shows a loss of tumor suppressor function, but in some cases possibly shows a gain of oncogenic function. In this study, we investigate relationships of out...

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Literature Corpus work: 512fa39c-3c7a-5952-bdf1-2661a6ed5a76
DOI: 10.21203/rs.3.rs-1851167/v1

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