Article
CK8/18 expression, the basal phenotype, and family history in identifying BRCA1-associated breast cancer in the Ontario site of the breast cancer family registry.
Cancer - 1 Apr 2011
Mulligan Anna Marie, Pinnaduwage Dushanthi, Bane Anita L, Bull Shelley B, O'Malley Frances P, Andrulis Irene L
Abstract excerpt
BACKGROUND: BRCA1-associated breast cancer had been shown to be morphologically and genetically distinct from sporadic cancers. The aim of this study was to determine the association of CK8/18 with BRCA1-associated tumors and if, by using CK8/18 and basal biomarkers in conjunction with morphologic features and family history characteristics, the specificity of the BRCA1-associated tumor profile in a...
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