Article
Prediction of BRCA1 germ-line mutation status in patients with breast cancer using histoprognosis grade, MS110, Lys27H3, vimentin, and KI67.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2013
Hassanein Mohamed, Huiart Laetitia, Bourdon Violaine, Rabayrol Laetitia, Geneix Jeanine, Nogues Catherine, Peyrat Jean Philippe, Gesta Paul, Meynard Paule, Dreyfus Helene, Petrot Dominique, Lidereau Rosette, Noguchi Tetsuro, Eisinger François, Extra Jean Marc, Viens Patrice, Jacquemier Jocelyne, Sobol Hagay
Abstract excerpt
Family structure, lack of reliable information, cost, and delay are usual concerns when deciding to perform BRCA analyses. Testing breast cancer tissues with four antibodies (MS110, lys27H3, vimentin, and KI67) in addition to grade evaluation enabled us to rapidly select patients for genetic test...
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