Article
Basal cytokeratins in breast tumours among BRCA1, BRCA2 and mutation-negative breast cancer families.
Breast cancer research : BCR - 1 Jan 2008
Eerola Hannaleena, Heinonen Mira, Heikkilä Päivi, Kilpivaara Outi, Tamminen Anitta, Aittomäki Kristiina, Blomqvist Carl, Ristimäki Ari, Nevanlinna Heli
Abstract excerpt
INTRODUCTION: Finding new immunohistochemical markers that are specific to hereditary breast cancer could help us to select candidates for BRCA1/BRCA2 mutation testing and to understand the biological pathways of tumour development. METHODS: Using breast cancer tumour microarrays, immunohistochemical expression of cytokeratin (CK)-5/6, CK-14 and CK-17 was evaluated in breast tumours from BRCA1 families (n = 46),...
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