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Article

Pathologic features and immunophenotype of estrogen receptor-positive breast cancers in BRCA1 mutation carriers.

The American journal of surgical pathology - 1 Oct 2012

Kaplan Jennifer S, Schnitt Stuart J, Collins Laura C, Wang Yihong, Garber Judy E, Montgomery Kelli, West Robert B, Krag Karen, Fetten Katharina, Lincoln Anne, Tung Nadine M

Abstract excerpt

Although most breast cancers in BRCA1 mutation carriers are estrogen receptor negative (ER-) with a basal-like phenotype, up to one third are ER positive (ER+). Little is known about the characteristics of this subgroup. To address this, we compared histologic and immunophenotypic features of 60 BRCA1-related ER+ breast cancers with those of 85 BRCA1-related ER- cancers and 174 matched ER+ sporadic cancers. ER+...

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Source

Identifiers

PMID: 22613997
DOI: 10.1097/PAS.0b013e31825789ed

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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