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Article

Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990

Zinoni F, Heider J, Böck A

Abstract excerpt

The fdhF gene encoding the 80-kDa selenopolypeptide subunit of formate dehydrogenase H from Escherichia coli contains an in-frame TGA codon at amino acid position 140, which encodes selenocysteine. We have analyzed how this UGA "sense codon" is discriminated from a UGA codon signaling polypeptide chain termination. Deletions were introduced from the 3' side into the fdhF gene and the truncated 5' segments were...

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Identifiers

PMID: 2141170
DOI: 10.1073/pnas.87.12.4660
PMCID: PMC54176

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Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine.PMID 2141170Read ↗

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