Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Factors and selenocysteine insertion sequence requirements for the synthesis of selenoproteins from a gram-positive anaerobe in Escherichia coli.

Applied and environmental microbiology - 1 Mar 2008

Gursinsky Torsten, Gröbe Daniel, Schierhorn Angelika, Jäger Jana, Andreesen Jan R, Söhling Brigitte

Abstract excerpt

Selenoprotein synthesis in Escherichia coli strictly depends on the presence of a specific selenocysteine insertion sequence (SECIS) following the selenocysteine-encoding UGA codon of the respective mRNA. It is recognized by the selenocysteine-specific elongation factor SelB, leading to cotranslational insertion of selenocysteine into the nascent polypeptide chain. The synthesis of three different selenoproteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pairing
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Codon, Terminator

Share to Escherichia coli

Share to Mass Spectrometry

Share to RNA, Transfer, Amino Acid-Specific

Share to Selenocysteine

Share to Selenoproteins

Source

Open in PubMed Open full text

Identifiers

PMID: 18165360
DOI: 10.1128/AEM.02238-07
PMCID: PMC2258645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Factors and selenocysteine insertion sequence requirements for the synthesis of selenoproteins from a gram-positive anaerobe in Escherichia coli.PMID 18165360Read ↗

Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNACys and elongation factor SelB.Semantic proximity Read ↗

Formation of a Ternary Complex for Selenocysteine Biosynthesis in Bacteria.Semantic proximity Read ↗

Engineering the elongation factor Tu for efficient selenoprotein synthesis.Semantic proximity Read ↗

Mechanism and regulation of selenoprotein synthesis.Semantic proximity Read ↗

Genes coding for the selenocysteine-inserting tRNA species from Desulfomicrobium baculatum and Clostridium thermoaceticum: structural and evolutionary implications.Semantic proximity Read ↗

Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation.Semantic proximity Read ↗

The mycobacterial selenocysteine machinery: presence and expressionSemantic proximity Read ↗

The efficiency of Escherichia coli selenocysteine insertion is influenced by the immediate downstream nucleotide.Semantic proximity Read ↗

Revised Escherichia coli selenocysteine insertion requirements determined by in vivo screening of combinatorial libraries of SECIS variants.Semantic proximity Read ↗

Genetic probing of the interaction between the translation factor SelB and its mRNA binding element in Escherichia coli.Semantic proximity Read ↗

Direct detection of potential selenium delivery proteins by using an Escherichia coli strain unable to incorporate selenium from selenite into proteins.Semantic proximity Read ↗

A synthetic tRNA for EF-Tu mediated selenocysteine incorporation in vivo and in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.