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Article

Mutagenesis of selC, the gene for the selenocysteine-inserting tRNA-species in E. coli: effects on in vivo function.

Nucleic acids research - 11 Dec 1990

Baron C, Heider J, Böck A

Abstract excerpt

The selenocysteine-inserting tRNA (tRNA(Sec)) of E. coli differs in a number of structural features from all other elongator tRNA species. To analyse the functional implications of the deviations from the consensus, these positions have been reverted to the canonical configuration. The following results were obtained: (i) inversion of the purine/pyrimidine pair at position 11/24 and change of the purine at...

Topics

Anticodon
Base Sequence
Cloning, Molecular
Consensus Sequence
Cysteine
Escherichia coli
Formate Dehydrogenases
Genes, Bacterial
Molecular Sequence Data
Mutagenesis, Insertional
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Conformation

RNA, Bacterial

RNA, Transfer, Amino Acid-Specific

Selenium

Selenocysteine

Source

Open in PubMed Open full text

Identifiers

PMID: 1702199
DOI: 10.1093/nar/18.23.6761
PMCID: PMC332728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1702199-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Mutagenesis of selC, the gene for the selenocysteine-inserting tRNA-species in E. coli: effects on in vivo function.PMID 1702199Read ↗

The length of the aminoacyl-acceptor stem of the selenocysteine-specific tRNA(Sec) of Escherichia coli is the determinant for binding to elongation factors SELB or Tu.Semantic proximity Read ↗

Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNACys and elongation factor SelB.Semantic proximity Read ↗

Genes coding for the selenocysteine-inserting tRNA species from Desulfomicrobium baculatum and Clostridium thermoaceticum: structural and evolutionary implications.Semantic proximity Read ↗

The bulged nucleotide in the Escherichia coli minimal selenocysteine insertion sequence participates in interaction with SelB: a genetic approach.Semantic proximity Read ↗

A homozygous mutation in the human selenocysteine tRNA gene impairs UGA recoding activity and selenoproteome regulation by selenium.Semantic proximity Read ↗

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In vitro synthesis of selenocysteinyl-tRNA(UCA) from seryl-tRNA(UCA): involvement and characterization of the selD gene product.Semantic proximity Read ↗

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