Article
A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21.
The British journal of dermatology - 1 Mar 2011
Warren R B, Smith R L, Flynn E, Bowes J, Eyre S, Worthington J, Barton A, Griffiths C E M
Abstract excerpt
BACKGROUND: Many autoimmune diseases share common susceptibility loci suggesting similar underlying cellular mechanisms involved in disease expression. OBJECTIVES: The purpose of this investigation was to study 21 genetic variants in 14 genes that are confirmed autoimmune loci in a cohort of patients with early-onset psoriasis. METHODS: Patients with early-onset psoriasis (n = 750) and controls (n = 3531) were...
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