Article
Confirmation of an association between rs6822844 at the Il2-Il21 region and multiple autoimmune diseases: evidence of a general susceptibility locus.
Arthritis and rheumatism - 1 Feb 2010
Maiti Amit K, Kim-Howard Xana, Viswanathan Parvathi, Guillén Laura, Rojas-Villarraga Adriana, Deshmukh Harshal, Direskeneli Haner, Saruhan-Direskeneli Güher, Cañas Carlos, Tobön Gabriel J, Sawalha Amr H, Cherñavsky Alejandra C, Anaya Juan-Manuel, Nath Swapan K
Abstract excerpt
OBJECTIVE: Autoimmune diseases often have susceptibility genes in common, indicating similar molecular mechanisms. Increasing evidence suggests that rs6822844 at the IL2-IL21 region is strongly associated with multiple autoimmune diseases in individuals of European descent. This study was undertaken to attempt to replicate the association between rs6822844 and 6 different immune-mediated diseases in non-European...
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