Article
Identification of loci associated with late-onset psoriasis using dense genotyping of immune-related regions.
The British journal of dermatology - 1 Apr 2015
Hébert H L, Bowes J, Smith Rh Ll, Flynn E, Parslew R, Alsharqi A, McHugh N J, Barker J N W N, Griffiths C E M, Barton A, Warren R B
Abstract excerpt
BACKGROUND: Chronic plaque psoriasis can be subdivided into two groups according to the age of onset: type 1 (early onset, before 40 years) and type 2 (late onset, at or beyond 40 years). So far, 36 genetic loci have been associated with early-onset psoriasis in genome-wide association studies of white populations, while few studies have investigated genetic susceptibility to late-onset psoriasis. OBJECTIVES: To...
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