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Article

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.

Experimental dermatology - 1 Jul 2015

Kunz Manfred, König Inke R, Schillert Arne, Kruppa Jochen, Ziegler Andreas, Grallert Harald, Müller-Nurasyid Martina, Lieb Wolfgang, Franke Andre, Ranki Annamari, Panelius Jaana, Koskenmies Sari, Hasan Taina, Kere Juha, Rönn Ann-Charlotte, Simon Jan C, Schmidt Enno, Wenzel Joerg, Tüting Thomas, Landsberg Jennifer, Zeller Tanja, Blankenberg Stefan, Gläser Regine, Patsinakidis Nikolaos, Kuhn Annegret, Ibrahim Saleh M

Abstract excerpt

Cutaneous lupus erythematosus (CLE) is a chronic autoimmune disease of the skin with typical clinical manifestations. Here, we genotyped 906 600 single nucleotide polymorphisms (SNPs) in 183 CLE cases and 1288 controls of Central European ancestry. Replication was performed for 13 SNPs in 219 case subjects and 262 controls from Finland. Association was particularly pronounced at 4 loci, all with genomewide...

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Source

Identifiers

PMID: 25827949
DOI: 10.1111/exd.12708

Genes

RPP21
TRIM39
MICA
MICB
MSH5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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