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Article

Multi-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis.

Journal of translational medicine - 30 Jan 2025

Zhang Min, Su Wenting, Deng Jiahui, Zhai Bin, Zhu Gaizhi, Gao Ran, Zeng Qi, Qiu Jinming, Bian Ziqing, Xiao He, Luan Guoming, Wang Renxi

Abstract excerpt

BACKGROUND: Psoriasis is a common chronic, recurrent, immune-mediated disease involved in the skin or joints or both. However, deeper insight into the genetic susceptibility of psoriasis is still unclear. METHODS: Here we performed the largest multi-ancestry meta-analysis of genome-wide association study including 28,869 psoriasis cases and 443,950 healthy controls. RESULTS: We identified 74 genome-wide...

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Identifiers

PMID: 39885523
DOI: 10.1186/s12967-024-06015-8
PMCID: PMC11783861

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