Article
Autoregulation of convergent RNAi genes in fission yeast.
Genes & development - 15 Mar 2011
Gullerova Monika, Moazed Danesh, Proudfoot Nick J
Abstract excerpt
RNAi plays a central role in the regulation of eukaryotic genes. In Schizosaccharomyces pombe fission yeast, RNAi involves the formation of siRNA from dsRNA that acts to establish and maintain heterochromatin over centromeres, telomeres, and mating loci. We showed previously that transient heterochromatin also forms over S. pombe convergent genes (CGs). Remarkably, most RNAi genes are themselves convergent. We...
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