Article
RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe.
Biochemical and biophysical research communications - 7 Feb 2014
Smialowska Agata, Djupedal Ingela, Wang Jingwen, Kylsten Per, Swoboda Peter, Ekwall Karl
Abstract excerpt
RNA interference (RNAi) is a gene silencing mechanism conserved from fungi to mammals. Small interfering RNAs are products and mediators of the RNAi pathway and act as specificity factors in recruiting effector complexes. The Schizosaccharomyces pombe genome encodes one of each of the core RNAi proteins, Dicer, Argonaute and RNA-dependent RNA polymerase (dcr1, ago1, rdp1). Even though the function of RNAi in...
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