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Article

RNA interference is essential for cellular quiescence.

Science (New York, N.Y.) - 11 Nov 2016

Roche B, Arcangioli B, Martienssen R A

Abstract excerpt

Quiescent cells play a predominant role in most organisms. Here we identify RNA interference (RNAi) as a major requirement for quiescence (G0 phase of the cell cycle) in Schizosaccharomyces pombe RNAi mutants lose viability at G0 entry and are unable to maintain long-term quiescence. We identified suppressors of G0 defects in cells lacking Dicer (dcr1Δ), which mapped to genes involved in chromosome segregation,...

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Identifiers

PMID: 27738016
DOI: 10.1126/science.aah5651
PMCID: PMC5858868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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