Article
RNAi-dependent formation of heterochromatin and its diverse functions.
Current opinion in genetics & development - 1 Apr 2010
Grewal Shiv Is
Abstract excerpt
Expression profiling of eukaryotic genomes has revealed widespread transcription outside the confines of protein-coding genes, leading to production of antisense and non-coding RNAs (ncRNAs). Studies in Schizosaccharomyces pombe and multicellular organisms suggest that transcription and ncRNAs provide a framework for the assembly of heterochromatin, which has been linked to various chromosomal processes. In...
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