Article
Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi.
Molecular cell - 3 Aug 2007
Colmenares Serafin U, Buker Shane M, Buhler Marc, Dlakić Mensur, Moazed Danesh
Abstract excerpt
The fission yeast centromeric repeats are transcribed and ultimately processed into small interfering RNAs (siRNAs) that are required for heterochromatin formation. siRNA generation requires dsRNA synthesis by the RNA-directed RNA polymerase complex (RDRC) and processing by the Dicer ribonuclease...
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