Article
ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe.
Molecular biology of the cell - 1 Mar 2004
Carmichael Jon B, Provost Patrick, Ekwall Karl, Hobman Tom C
Abstract excerpt
In the fission yeast Schizosaccharomyces pombe, three genes that function in the RNA interference (RNAi) pathway, ago1+, dcr1+, and rdp1+, have recently been shown to be important for timely formation of heterochromatin and accurate chromosome segregation. In the present study, we present evidence that null mutants for ago1+ and dcr1+ but not rdp1+, exhibit abnormal cytokinesis, cell cycle arrest deficiencies,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.