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Article

A haplotype of cyclooxygenase-2 gene is associated with idiopathic pulmonary fibrosis.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Jul 2010

Xaubet A, Fu W J, Li M, Serrano-Mollar A, Ancochea J, Molina-Molina M, Rodriguez-Becerra E, Morell F, Rodríguez-Arias J M, Pereda J, Casanova A, Molins L, Picado C

Abstract excerpt

BACKGROUND: Cyclooxygenase-2, a key regulatory enzyme in the synthesis of the antifibrotic agent prostaglandin E2, is downregulated in lung tissue from patients with idiopathic pulmonary fibrosis. OBJECTIVE: To investigate the association between COX2.3050 (G --> C), COX2.8473 (C --> T) and COX2.926 (G --> C) single nucleotide polymorphisms (SNP) and the susceptibility to idiopathic pulmonary fibrosis and the...

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PMID: 21319594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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