Article
A genetic polymorphism in prostaglandin synthase 2 (8473, T-->C) and the risk of lung cancer.
Cancer letters - 8 Aug 2005
Sørensen Mette, Autrup Herman, Tjønneland Anne, Overvad Kim, Raaschou-Nielsen Ole
Abstract excerpt
Prostaglandin synthase 2 (PTGS2) mediated production of prostaglandins is an important step in the inflammatory response. In a population-based case-cohort study, we investigated the relationship between lung cancer and a polymorphism in PTGS2 at site 8473. Among 54,220 cohort members, 265 lung cancer cases and a comparison group of 272 individuals were identified. We found no overall significant association...
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