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Article

Functional effects and gender association of COX-2 gene polymorphism G-765C in bronchial asthma.

The Journal of allergy and clinical immunology - 1 Aug 2004

Szczeklik Wojciech, Sanak Marek, Szczeklik Andrew

Abstract excerpt

BACKGROUND: Prostaglandins, generated via the COX pathways, are essential mediators of inflammation in bronchial asthma. The promoter polymorphism of COX-2 gene (G-765C), which might affect binding of transcription factors, has recently been described OBJECTIVE: To study distribution and function of the genetic COX-2 variant in patients with asthma compared with healthy controls. METHODS: Three groups of adults...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15316498
DOI: 10.1016/j.jaci.2004.05.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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