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Article

Polymorphisms in cyclooxygenase-2 gene and risk of developing coal workers' pneumoconiosis: a case-control study.

American journal of industrial medicine - 1 Aug 2014

Bian Lu-Qin, Mao Ling, Shi Jin, Bi Ying

Abstract excerpt

BACKGROUND: Coal workers' pneumoconiosis (CWP) is characterized by progressive pulmonary fibrosis. Inflammation is crucial in the host response to silica and it contributes to pulmonary fibrosis. Cyclooxygenase-2 is involved in this process. The association between single-nucleotide polymorphisms in cyclooxygenase-2 gene with pneumoconiosis risk was investigated. METHODS: An association study was conducted by...

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PMID: 24899082
DOI: 10.1002/ajim.22335

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