Article
The cyclooxygenase-2-765C promoter polymorphism protects against the development of chronic obstructive pulmonary disease.
Respiratory medicine - 1 Mar 2011
Wu Lian, Merrilees Mervyn, Young Robert P, Black Peter N
Abstract excerpt
BACKGROUND: Susceptibility to Chronic Obstructive Pulmonary Disease (COPD) has a genetic component. We undertook a study to determine if a genetic variant of the gene encoding the cyclooxygenase-2 gene influences the likelihood of developing COPD. METHODS: In a case control study the frequency of a single nucleotide polymorphism in the promoter region of the cyclooxygenase-2 gene (-765 G → C) was determined in...
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