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Article

Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.

Pharmacogenomics - 1 Dec 2007

Skarke Carsten, Schuss Patrick, Kirchhof Anja, Doehring Alexandra, Geisslinger Gerd, Lötsch Jörn

Abstract excerpt

INTRODUCTION: Genetic variants in the prostaglandin-endoperoxide synthase 2 (PTGS2) gene, which codes for COX-2, have been identified to modulate the response to COX-2-inhibiting drugs and to be possible risk factors for the incidence or prognosis of cardiovascular or neoplastic diseases, Alzheimer's disease, multiple sclerosis, asthma or osteoarthritis. Clinical evidence thus suggests a clinical importance of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18085997
DOI: 10.2217/14622416.8.12.1643

Genes

PTGS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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