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Article

MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis.

Human genetics - 1 Dec 2008

Checa Marco, Ruiz Víctor, Montaño Martha, Velázquez-Cruz Rafael, Selman Moisés, Pardo Annie

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disorder of unknown etiology and unclear pathogenesis. Matrix metalloproteinase-1 (MMP-1) is strongly upregulated and may contribute to the abnormal remodeling that characterizes the disease. We conducted a case-control study of 130 IPF patients and 305 healthy controls to investigate associations between two polymorphisms of the MMP-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18853190
DOI: 10.1007/s00439-008-0571-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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