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Article

Insm1 promotes the transition of olfactory progenitors from apical and proliferative to basal, terminally dividing and neuronogenic.

Neural development - 1 Feb 2011

Rosenbaum Jason N, Duggan Anne, García-Añoveros Jaime

Abstract excerpt

BACKGROUND: Insm1 is a zinc-finger transcription factor transiently expressed throughout the developing nervous system in late progenitors and nascent neurons. Insm1 is also highly expressed in medulloblastomas and other neuroendocrine tumors. RESULTS: We generated mice lacking the Insm1 gene and used them to elucidate its role in neurogenic proliferation of the embryonic olfactory epithelium. We found that...

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Source

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Identifiers

PMID: 21284846
DOI: 10.1186/1749-8104-6-6
PMCID: PMC3057173

Genes

ASCL1
NEUROD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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