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Article

Slit/Robo signaling modulates the proliferation of central nervous system progenitors.

Neuron - 18 Oct 2012

Borrell Víctor, Cárdenas Adrián, Ciceri Gabriele, Galcerán Joan, Flames Nuria, Pla Ramón, Nóbrega-Pereira Sandrina, García-Frigola Cristina, Peregrín Sandra, Zhao Zhen, Ma Le, Tessier-Lavigne Marc, Marín Oscar

Abstract excerpt

Neurogenesis relies on a delicate balance between progenitor maintenance and neuronal production. Progenitors divide symmetrically to increase the pool of dividing cells. Subsequently, they divide asymmetrically to self-renew and produce new neurons or, in some brain regions, intermediate progenitor cells (IPCs). Here we report that central nervous system progenitors express Robo1 and Robo2, receptors for Slit...

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Identifiers

PMID: 23083737
DOI: 10.1016/j.neuron.2012.08.003
PMCID: PMC4443924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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