Article
Id4 is required for the correct timing of neural differentiation.
Developmental biology - 15 Apr 2005
Bedford Lynn, Walker Robert, Kondo Toru, van Crüchten Ingeborg, King Emerson R, Sablitzky Fred
Abstract excerpt
Complex intrinsic and extrinsic mechanisms determine neural cell fate during development of the nervous system. Using Id4 deficient mice, we show that Id4 is required for normal development of the central nervous system (CNS), timing neural differentiation in the developing forebrain. In the absence of Id4, the ventricular zone of the neocortex, future hippocampus as well as lateral and medial ganglionic...
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