Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pdm and Castor close successive temporal identity windows in the NB3-1 lineage.

Development (Cambridge, England) - 1 Nov 2008

Tran Khoa D, Doe Chris Q

Abstract excerpt

Neurogenesis in Drosophila and mammals requires the precise integration of spatial and temporal cues. In Drosophila, embryonic neural progenitors (neuroblasts) sequentially express the transcription factors Hunchback, Kruppel, Pdm1/Pdm2 (Pdm) and Castor as they generate a stereotyped sequence of neuronal and glial progeny. Hunchback and Kruppel specify early temporal identity in two posterior neuroblast lineages...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Cell Lineage
Share to Central Nervous System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Homeodomain Proteins

Share to Kruppel-Like Transcription Factors

Share to Motor Neurons

Share to POU Domain Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 18832394
DOI: 10.1242/dev.024349
PMCID: PMC3989073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pdm and Castor close successive temporal identity windows in the NB3-1 lineage.PMID 18832394Read ↗

Pdm and Castor specify late-born motor neuron identity in the NB7-1 lineage.Semantic proximity Read ↗

Notch controls early temporal factor expression to control timing of Mushroom body neuroblast apoptosisSemantic proximity Read ↗

seven-up Controls switching of transcription factors that specify temporal identities of Drosophila neuroblasts.Semantic proximity Read ↗

Regulation of neuroblast competence in Drosophila.Semantic proximity Read ↗

Cellular diversity in the developing nervous system: a temporal view from Drosophila.Semantic proximity Read ↗

Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage.Semantic proximity Read ↗

Hierarchical deployment of factors regulating temporal fate in a diverse neuronal lineage of the Drosophila central brain.Semantic proximity Read ↗

Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors.Semantic proximity Read ↗

Drosophila neuroblast 7-3 cell lineage: a model system for studying programmed cell death, Notch/Numb signaling, and sequential specification of ganglion mother cell identity.Semantic proximity Read ↗

Drosophila Polycomb complexes restrict neuroblast competence to generate motoneurons.Semantic proximity Read ↗

Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal.Semantic proximity Read ↗

Patterning mechanisms diversify neuroepithelial domains in the Drosophila optic placode.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.