Article
Id4 regulates neural progenitor proliferation and differentiation in vivo.
Development (Cambridge, England) - 1 Nov 2004
Yun Kyuson, Mantani Akio, Garel Sonia, Rubenstein John, Israel Mark A
Abstract excerpt
The mechanisms that determine whether a precursor cell re-enters the cell cycle or exits and differentiates are crucial in determining the types and numbers of cells that constitute a particular organ. Here, we report that Id4 is required for normal brain size, and regulates lateral expansion of the proliferative zone in the developing cortex and hippocampus. In its absence, proliferation of stem cells in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.