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Article

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4.

Developmental biology - 1 Feb 2009

Chen Binglai, Kim Eun-Hee, Xu Pin-Xian

Abstract excerpt

Mouse olfactory epithelium (OE) originates from ectodermally derived placode, the olfactory placode that arises at the anterior end of the neural plate. Tissue grafting and recombination experiments suggest that the placode is derived from a common preplacodal domain around the neural plate and its development is directed by signals arising from the underlying mesoderm and adjacent neuroectoderm. In mice, loss of...

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Identifiers

PMID: 19027001
DOI: 10.1016/j.ydbio.2008.10.039
PMCID: PMC7058120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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