Article
Functional genomics identifies neural stem cell sub-type expression profiles and genes regulating neuroblast homeostasis.
Developmental biology - 1 Jan 2012
Carney Travis D, Miller Michael R, Robinson Kristin J, Bayraktar Omer A, Osterhout Jessica A, Doe Chris Q
Abstract excerpt
The Drosophila larval central brain contains about 10,000 differentiated neurons and 200 scattered neural progenitors (neuroblasts), which can be further subdivided into ~95 type I neuroblasts and eight type II neuroblasts per brain lobe. Only type II neuroblasts generate self-renewing intermediate neural progenitors (INPs), and consequently each contributes more neurons to the brain, including much of the...
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