Article
Genome-wide quantitative assessment of variation in DNA methylation patterns.
Nucleic acids research - 1 May 2011
Xie Hehuang, Wang Min, de Andrade Alexandre, Bonaldo Maria de F, Galat Vasil, Arndt Kelly, Rajaram Veena, Goldman Stewart, Tomita Tadanori, Soares Marcelo B
Abstract excerpt
Genomic DNA methylation contributes substantively to transcriptional regulations that underlie mammalian development and cellular differentiation. Much effort has been made to decipher the molecular mechanisms governing the establishment and maintenance of DNA methylation patterns. However, little is known about genome-wide variation of DNA methylation patterns. In this study, we introduced the concept of...
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