Article
DNA methylation entropy is associated with DNA sequence features and developmental epigenetic divergence
2022-12-21
Abstract excerpt
Epigenetic information defines tissue identity and is largely inherited in development through DNA methylation. While studied mostly for mean differences, methylation also encodes stochastic change, defined as entropy in information theory. Analyzing allelespecific methylation in 48 human tissue sample datasets, we find that methylation entropy is associated with specific DNA binding motifs, regulatory DNA, and Cp...
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Identifiers and source
- Literature Corpus work
- 9cbc9032-ac00-52af-a7e0-c068cde2d6fe
- DOI
- 10.1101/2022.12.21.521278