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Article

Expression of a transgenic class II Ab gene confers susceptibility to collagen-induced arthritis.

European journal of immunology - 1 Jul 1994

Brunsberg U, Gustafsson K, Jansson L, Michaëlsson E, Ahrlund-Richter L, Pettersson S, Mattsson R, Holmdahl R

Abstract excerpt

The major histocompatibility complex (MHC) class II region is assumed to influence autoimmune diseases such as rheumatoid arthritis. In the mouse, the H-2q haplotype is associated with susceptibility to collagen-induced arthritis, while the H-2p haplotype is not. The class II A molecules of these...

Topics

Animals
Antigen Presentation
Arthritis
Autoimmune Diseases
Base Sequence
Collagen
Genetic Predisposition to Disease
Histocompatibility Antigens Class II
Immunohistochemistry
Mice
Mice, Inbred C3H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mice, Inbred CBA

Mice, Transgenic

Molecular Sequence Data

Source

Identifiers

PMID: 8026530
DOI: 10.1002/eji.1830240736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8026530-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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