Article
Analysis of ENU-induced mutations at the Adh locus in Drosophila melanogaster.
Mutation research - 1 Jul 1990
Fossett N G, Arbour-Reily P, Kilroy G, McDaniel M, Mahmoud J, Tucker A B, Chang S H, Lee W R
Abstract excerpt
N-Ethyl-N-nitrosourea (ENU) was used to induce mutations in the Drosophila melanogaster, alcohol dehydrogenase (Adh) gene. Flies were treated with ENU and mated to homozygous intragenic Adh null mutants; Adh null mutations were selected by exposure of the F1 generation to 1-penten-3-ol. Fourteen Adh null mutations were recovered which included 11 from spermatozoa, 2 from oocytes and 1 from a premeiotic...
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