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Article

Efficient recovery of ENU-induced mutations from the zebrafish germline.

Genetics - 1 Apr 1994

Solnica-Krezel L, Schier A F, Driever W

Abstract excerpt

We studied the efficiency with which two chemical mutagens, ethyl methanesulfonate (EMS) and N-ethyl-N-nitrosourea (ENU) can induce mutations at different stages of spermatogenesis in zebrafish (Brachydanio rerio). Both EMS and ENU induced mutations at high rates in post-meiotic germ cells, as indicated by the incidence of F1 progeny mosaic for the albino mutation. For pre-meiotic germ cells, however, only ENU...

Topics

Alleles
Animals
Ethyl Methanesulfonate
Ethylnitrosourea
Female
Fertility
Genes, Dominant
Genes, Lethal
Male
Meiosis
Mosaicism
Mutagens
Spermatozoa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Zebrafish

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Identifiers

PMID: 8013916
DOI: 10.1093/genetics/136.4.1401
PMCID: PMC1205920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8013916-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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